Sale Sharks centre Manu Tuilagi has handed Steve Borthwick's England side a significant boost as he returns from injury ahead of their trip to Murrayfield to face Scotland.
The 32-year-old is joined by Bath's Ollie Lawrence and Harlequins Marcus Smith, who will both continue their rehab within the England set-up.
England will face Scotland on February 24th with kick-off scheduled for 16.45.
Dropping out of the squad are hooker Jamie Blamire, flanker Tom Pearson and utility back Oscar Beard drop out.
England's Six Nations squad
Forwards: Ollie Chessum, Dan Cole, Alex Coles, Luke Cowan-Dickie, Chandler Cunningham-South, Ben Curry, Theo Dan, Alex Dombrandt, Ben Earl, Charlie Ewels, Ellis Genge, Jamie George (capt), Joe Heyes, Maro Itoje, Joe Marler, Beno Obano, George Martin, Ethan Roots, Will Stuart, Sam Underhill.
Backs: Danny Care, Elliot Daly, Fraser Dingwall, Immanuel Feyi-Waboso, George Ford, Tommy Freeman, George Furbank, Alex Mitchell, Will Muir, Max Ojomoh, Tom Roebuck, Henry Slade, Fin Smith, Ben Spencer, Freddie Steward, Manu Tuilagi.
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